4-HO-DET | Your Gateway to a Balanced Psychedelic Experience

Psychedelic Precision in Every Dose

Contains No: Psilocybin, Psilocin or Amanita Muscaria

4-HO-DET is a different molecule in the tryptamine family

What is 4-HO-DET?

4-HO-DET (4-Hydroxy-N,N-diethyltryptamine), also known as Ethocin, is a synthetic psychedelic compound in the tryptamine family. Structurally similar to psilocin (4-HO-DMT), it’s known for its smoother, more controllable

experience with vivid psychedelic visuals, increased emotional openness, and introspective thought. Delivered in pharmaceutical-style tablets, this

compound offers a measured, modern alternative to traditional psychedelics like psilocybin mushrooms.

How Potent is 5mg of 4-HO-DET and How Much Should I Take at First?

A 5mg dose is considered a light to moderate experience. First-time users should start with 3–5mg to assess sensitivity. Effects can begin within 20–45 minutes and last 4–6 hours.

Always start low and go slow, especially when gauging individual response.

Dosage & Potency

Each tablet contains 5mg of 4-HO-DET – a light to moderate dose ideal for both beginner and experienced psychonauts.

✅ New users: Start with ½ tablet (2.5mg)

✅ Microdosing: Take 0.5–2mg, depending on tolerance

✅ Macrodosing: 5–15mg range (1–3 tablets) for full effects

Why Tablets?

• 🔬 Lab-tested accuracy: Consistent experience every time

• ⏱ Fast-acting: Onset within 30–45 minutes
• 📦 Discreet: Easy to store, transport, and dose

• ⚖ Precision: Perfect for microdosing or entering a new dimension

How Does 4-HO-DET Compare to 7-Hydroxy?

While 4-HO-DET is well-studied and reliably psychoactive, 7-Hydroxy compounds are less researched and more variable in their effects. 4-HO-DET offers a clearer, more euphoric experience, while 7-Hydroxy compounds may feel heavier, less emotionally engaging, and more sedative in some cases.

How Does 4-HO-DET Compare to Other Substances?

Compound	Experience	Duration
4-HO-DET	Clean visuals, smooth onset, clear headspace	4–6hours
4-HO-DMT	Heavier trip, more body load	4–5hours
7-Hydroxy	Less studied, often sedating	Varies
Psilocybin	Natural, spiritual, sometimes unpredictable	4–6hours

What Do the Effects of 4-HO-DET Feel Like?

• Enhanced mood and euphoria

• Dreamlike visuals and color enhancement

• Increased introspection and empathy

• Cognitive expansion without overwhelming intensity

• Grounded body high, clean and energizing

What is the History of 4-HO-DET?

Originally designated Lab Code CZ-74 in the late 1950s by legendary chemists Albert Hofmann and Franz Troxler, 4-HO-DET has deep roots in the golden age of psychedelic research. Paired with its phosphoryloxy analog CEY-19, this compound was explored in human clinical trials during the 1960s by pioneering German scientists Hanscarl Leuner and G. Baer.

Known for delivering entheogenic effects that bridge the gap between psilocybin and LSD, 4-HO-DET offers a unique experience that many describe as clearer, smoother, and more manageable than traditional psychedelics.

While individual responses may vary, seasoned psychonauts often prefer its gentle onset, visual clarity, and introspective depth, making it an appealing option for those seeking a balanced and insightful journey.

What States is 4-HO-DET Legal In?

✅ Federally unscheduled in the U.S.

4-HO-DET exists in a legal gray area and is not scheduled federally in the U.S. However, some states (like Louisiana or Florida) may have analog laws or prohibitions. Always check local laws before purchase or use.

Will 4-HO-DET Cause Me to Fail a Drug Test?

Standard drug tests do not screen for tryptamines like 4-HO-DET. However, specialized tests could potentially detect it, so caution is advised if you are subject to strict drug testing environments.

What Are the Benefits of Microdosing 4-HO-DET?

• Boosts mood and reduced anxiety without sedation

• Increased focus and creativity, and task management

• Boost Motivation and help with social ease

• Cognitive clarity without intoxication

• Subtle enhancement of perception

Typical microdose range: 0.5–2mg

How Does 4-HO-DET Compare to 4-HO-DMT (Psilocin)?

4-HO-DET is less intense and more predictable than psilocin. It offers a longer duration and gentler onset, with fewer fluctuations in intensity. Users often describe it as more cerebral, lucid, and balanced.

What Products Does 4-HO-DET Compare To?

4-HO-DET is comparable to:

• Psilocybin mushrooms (though more consistent)

• LSD (but more emotional and visual)

• 4-AcO-DMT (but with less sedation and more clarity)

Microdosing: 4-HO-DET vs 7-Hydroxy Compounds

4-HO-DET: Enhances mood, focus, and empathy with low perceptual distortion.

7-Hydroxy: Less consistent; may feel duller or more sedating. Limited research available.

Winner for microdosing: 4-HO-DET for its balance, clarity, and reliable effects.

4-HO-DET vs 7-OH Microdosing

Feature	4-HO-DET	7-Hydroxy Compounds
Research-backed	✅ Yes	❌ Limited
Mood enhancement	✅ Strong	⚠ Varies
Mental clarity	✅ Clear & present	⚠ Often foggy
Ideal format	✅ Tablet-friendly	❌ Rare in solid form

Key Selling Points

✔ Legal in many U.S. states (Check locally)

✔ Clean, euphoric psychedelic experience

✔ Ideal for both macrodosing and microdosing

✔ More predictable and refined than mushrooms

✔ Long shelf life and stable in formulation

✔ Backed by Shulgin’s original research

✔ Smooth onset and offset—no harsh comedown

Pharmaceutical-grade tablets for safe, accurate dosing.

What is 4-HYDROXY?
4-HYDROXY offers a refined psychedelic experience that’s smoother, clearer, and more manageable than traditional psilocybin. Structurally similar to psilocin, yet noticeably more calm and clean, 4-HO-DET delivers gentle visuals, enhanced creativity, and elevated awareness without the emotional overwhelm.

What are the Effects?
Enhanced color, patterns, and visual perception
Calm euphoria and emotional clarity
Cognitive expansion without mental chaos
A grounded body feel–light, clean, and energizing
Ideal for both Introspection and social exploration

How Does 4-HYDROXY Compare To 7-HYDROXY?
While 4-HYDROXY is well studied and reliably psychoactive, 7-HYDROXY compounds are less researched and more variable in their effects.